College football Week 10 picks from ESPN's College GameDay

As the Week 10 college football schedule begins today, the guys at ESPN's College GameDay reveal their final picks and predictions for the biggest games across the country.

While the team sits in Happy Valley, most of the attention is on the big matchup between Ohio State and Penn State, which will go a long way in determining the top of the Big Ten going forward.

But there are other games on the schedule today that will prove it, including another Big Ten matchup pitting No. 1 Oregon against a Michigan team that will play its best and an ACC game with Pittsburgh and SMU I hope to take a big step forward at this conference.

What can we look forward to as some impactful Week 10 games begin on Saturday?

Let's take a tour of the country and make our final picks for today's biggest games with the help of ESPN College GameDay analysts.

Pittsburgh at SMU: Nick Saban, Kirk Herbstreit and Lee Corso led the way, predicting the Mustangs would win at home and hand the Panthers their first loss of the season.

Louisville at Clemson: A unanimous decision in favor of the Tigers to continue their winning streak in this ACC home game.

Texas Tech at Iowa State: Likewise, the Cyclones remain undefeated and in the hunt for the Big 12 title with an expected win over the Red Raiders.

Wisconsin in Iowa: Nick Saban was the only one to give the Badgers a win over the Hawkeyes, who are currently undergoing a quarterback change.

Duke in Miami: Everyone on game day expects the Hurricanes offense to get the most out of the Blue Devils defense and stay perfect in this ACC setup.

Ole Miss at Arkansas: Saban, Herbstreit and Corso expect the Hogs to beat the Rebels at home, which will be a major upset that would end Ole Miss' playoff hopes.

Texas A&M at South Carolina: Guest player Keegan Michael Key takes on the Gamecocks to upset the Aggies and hand them their first SEC loss.

Ohio State and Penn State: Nick Saban and Pat McAfee are heading with the Nittany Lions to end their long losing streak against the Buckeyes, while Kirk Herbstreit and Desmond Howard remain loyal to his alma mater Ohio State.

Lee Corso's headwear selection: Ohio State over Penn State

Week 10 earnings predictions based on expert model

Spread Predictions for Week 10 Games

College football straight-up picks for Week 10

Week 10 schedule, best games to watch today

Ole Miss vs. Arkansas

Clemson vs. Louisville

Army vs. Air Force

Duke vs. Miami

Tennessee vs. Kentucky

Pittsburgh vs. SMU

Texas A&M vs. South Carolina

Oregon vs. Michigan

Georgia vs. Florida

Ohio State vs. Penn State

First place votes in parentheses

1.Oregon (61)
2. Georgia (1)
3. Penn State
4. Ohio State
5.Miami
6.Texas
7. Tennessee
8. Notre Dame
9.BYU
10. Texas A&M
T-11. Clemson/Iowa State
13.Indiana
14.Alabama
15. Boise State
16. LSU
17. Kansas State
18. Pittsburgh
19. Ole Miss
20. SMU
21st Army
22. Washington State
23.Colorado
24. Illinois
25. Missouri

More… ESPN Top 25 College Football Rankings for Week 10

–

More college football from SI: Top 25 rankings | schedule | teams

Follow College Football Headquarters: bookmark | Rankings | Selection